Nasal decolonization of Staphylococcus aureus with mupirocin: strengths, weaknesses and future prospects
نویسندگان
چکیده
منابع مشابه
Nasal decolonization of Staphylococcus aureus with mupirocin: strengths, weaknesses and future prospects
Staphylococcus aureus in the nose is a risk factor for endogenous staphylococcal infection. UK guidelines recommend the use of mupirocin for nasal decolonization in certain groups of patients colonized with methicillin-resistant S. aureus (MRSA). Mupirocin is effective at removing S. aureus from the nose over a few weeks, but relapses are common within several months. There are only a few prosp...
متن کاملEffect of Mupirocin Treatment in Eradication of Staphylococcus aureus Nasal Carriage among Intensive Care Unit Personnel
ABSTRACT Background and Objective: Staphylococcus aureus is the most common and important infectious agent. This bacterium can enter the bloodstream and cause some complications in the intensive care unit (ICU).This organism can frequently be found in the nose and transmitted by the carriers. This study aimed to determine the efficiency of eradicating S...
متن کاملDecolonization with Mupirocin and Subsequent Risk of Methicillin-Resistant Staphylococcus aureus Carriage in Veterans Affairs Hospitals
INTRODUCTION Hospital-acquired methicillin-resistant Staphylococcus aureus (MRSA) infections remain one of the leading causes of preventable patient mortality in the US. Eradication of MRSA through decolonization could prevent both MRSA infections and transmission; however, there is currently no consensus within the infectious disease community on the proper role of decolonization in the preven...
متن کاملPatient experience with mupirocin or povidone-iodine nasal decolonization.
Led by the federal government, the payers of health care are enacting policies designed to base provider reimbursement on the quality of care they render. This study evaluated and compared patient experiences and satisfaction with nasal decolonization with either nasal povidone-iodine (PI) or nasal mupirocin ointment (MO). A total of 1903 patients were randomized to undergo preoperative nasal d...
متن کاملAcquisition of high-level mupirocin resistance in CoNS following nasal decolonization with mupirocin.
OBJECTIVES The association between mupirocin use and plasmid-based high-level resistance development mediated through mupA in CoNS has not been quantified. We determined acquisition of mupirocin resistance in Staphylococcus aureus and CoNS in surgery patients treated peri-operatively with mupirocin. PATIENTS AND METHODS Patients admitted for surgery were treated with nasal mupirocin ointment ...
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ژورنال
عنوان ژورنال: Journal of Antimicrobial Chemotherapy
سال: 2009
ISSN: 0305-7453,1460-2091
DOI: 10.1093/jac/dkp159